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Breast Cancer

Trial ATNEC
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases at presentation after neoadjuvant chemotherapy

Click Here to view Cancer Research UK trial summary
Trial CAPItello-292
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital
Information

A Phase Ib/III, Open-label, Randomised Study of Capivasertib plus CDK4/6 Inhibitors and Fulvestrant versus CDK4/6 Inhibitors and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced, Unresectable or Metastatic Breast Cancer

Trial CT7001_003
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A Phase 1b/2 Open-label Study of Samuraciclib in Combination with Elacestrant in Participants with
Metastatic or Locally Advanced Hormone Receptor-positive and Human Epidermal Growth Factor
Receptor 2-negative Breast Cancer

Trial EndoNET
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital and Belfast City Hospital
Information

Randomised controlled trial evaluating effectiveness of neoadjuvant endocrine treatment in post-menopausal women

Trial HER2-RADiCAL
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

The HER2-RADiCAL study (Response ADaptive CAre pLan) – Tailoring treatment for HER2 positive early breast cancer

Click Here to view Cancer Research UK trial summary
Trial ModiFY Study
Cancer Type Breast Cancer, Head & Neck Cancer, Kidney Cancer, and Ovarian Cancer
Hospital(s) Belfast City Hospital
Information

The ModiFY Study: A phase 1/2, multicentre, open‐label study of Modi‐1 in patients with breast, head and neck, ovarian, or renal cancer

Trial OPTIMA
Cancer Type Breast Cancer
Hospital(s) Ulster Hospital
Information

Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis

Trial POETIC-A
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Pre-Operative Endocrine Therapy for Individualised Care with Abemaciclib

Click Here to view Cancer Research UK trial summary
Trial SMALL Trial
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital, Belfast City Hospital, and Craigavon Hospital
Information

A Phase III, randomised, multi-centre trial addressing overtreatment of small screen-detected breast cancer by comparing standard surgery versus minimally invasive vacuum-assisted excision

Trial TROPION - 03
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital
Information

A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Versus Investigator’s Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/or Axillary Lymph Nodes at Surgical Resection Following Neoadjuvant Systemic Therapy (TROPION-Breast03)