Gastrointestinal Cancer

Trial	DECIPHER
Cancer Type	Gastrointestinal, Oesophageal Cancer, and Stomach Cancer
Hospital(s)	Belfast City Hospital
Information	Developing ctDNA guided adjuvant therapy for gastrooesophageal cancer. A single arm phase II trial of trastuzumab deruxtecan in patients with gastrooesophageal adenocarcinoma cancer who are ctDNA and HER2 positive
Trial Open	Yes

Trial	DESTINY Gastric05
Cancer Type	Gastrointestinal and Stomach Cancer
Hospital(s)	Altnagelvin Hospital
Information	A Multicenter, Randomized, Open-label, Phase 3 Trial of Trastuzumab Deruxtecan (Enhertu®) Plus Chemotherapy Plus or Minus Pembrolizumab versus Chemotherapy Plus Trastuzumab Plus or Minus Pembrolizumab as First-line Treatment in Participants with Unresectable, Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction (GEJ) Cancer
Trial Open	Yes

Trial	ICHOR
Cancer Type	Gastrointestinal, Oesophageal Cancer, and Stomach Cancer
Hospital(s)	Belfast City Hospital
Information	Investigation of Circulating Haematological Biomarkers in Cancer
Trial Open	Yes