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Haematological Cancers

Trial AMMO
Cancer Type Haematological Cancers
Hospital(s) Belfast City Hospital
Information

A Randomised Phase II Study Of ASTX727 Versus Best Supportive Care In MDS/MPN Overlap Syndromes

Trial EXCALIBER
Cancer Type Haematological Cancers and Myeloma
Hospital(s) Belfast City Hospital
Information

A Phase 3, Two-Stage, Randomized, Multicenter, Open-Label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Subjects with Relapsed or Refractory Multiple Myeloma (RRMM)

Trial FEDORA
Cancer Type Haematological Cancers and Other Haematological
Hospital(s) Belfast City Hospital
Information

A Phase II Study To Evaluate The Tolerability, Safety And Activity Of Fedratinib Combined With Ropeginterferon Alfa-2b In Patients With Myelofibrosis

Trial MITHRIDATE
Cancer Type Haematological Cancers and Other Haematological
Hospital(s) Belfast City Hospital
Information

A phase III, randomised, open-label, Multicenter International Trial comparing ruxolitinib with either HydRoxycarbamIDe or interferon Alpha as first line ThErapy for high risk polycythemia vera

Trial MOSAICC
Cancer Type Haematological Cancers and Other Haematological
Hospital(s) Altnagelvin Hospital, Antrim Hospital, Belfast City Hospital, Craigavon Hospital, and Ulster Hospital
Information

MyeloprOliferative NeoplasmS An In-Depth Case-Control Study: A Case-Control Study Of Patients With Myeloproliferative Neoplasms And Non-Blood Relative/Friend Controls

Trial PRiZM+
Cancer Type Haematological Cancers and Lymphoma
Hospital(s) Belfast City Hospital
Information

A phase II platform study of zanubrutinib monotherapy and combination therapy for relapsed and refractory primary CNS lymphoma

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Trial PROMISE
Cancer Type Haematological Cancers and Other Haematological
Hospital(s) Belfast City Hospital
Information

Investigation Into The Combination Of PLX2853 With Ruxolitinib In Patients With Intermediate-2 Or High Risk Myelofibrosis Not Receiving An Adequate Response With Ruxolitinib Alone

Trial STELLAR
Cancer Type Haematological Cancers and Lymphoma
Hospital(s) Belfast City Hospital
Information

A phase II, randomiSed study of CHOP-R in combination with acalabruTinib comparEd to CHOP-R in patients with newLy diagnosed Richter’s Syndrome and a pLAtfoRm for initial investigations into activity of novel treatments in relapsed/refractory and newly diagnosed Richter’s Syndrome

Trial VICTOR
Cancer Type Haematological Cancers and Leukaemia
Hospital(s) Belfast City Hospital
Information

Venetoclax or Intensive Chemotherapy For Treatment of Favourable Risk Acute Myeloid Leukaemia: A Molecularly Guided Phase 2 Study

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